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Machine learning models for predicting Alzheimer's disease onset 5 years before clinical symptoms appear

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README.md

Alzheimer's ML Prediction

This project develops machine learning models for predicting Alzheimer's disease onset 5 years before clinical symptoms appear, using multi-modal data including genomics, cognitive assessments, and neuroimaging.

Features

  • Deep learning models trained on genomic sequences and SNP data
  • Time-series analysis of cognitive assessment scores
  • Convolutional neural networks for MRI image analysis
  • Ensemble methods combining multiple data modalities

Installation

pip install -r requirements.txt
python setup.py install

Usage

from alzheimers_ml import AlzheimerPredictor

predictor = AlzheimerPredictor()
prediction = predictor.predict(patient_data)
print(f"Risk score: {prediction.risk_score}")

Results

Our models achieve 87% accuracy in predicting Alzheimer's onset 5 years before clinical diagnosis, with particularly strong performance when combining genomic and imaging data.

License

This project is licensed under the MIT License - see the LICENSE file for details.

About

Machine learning models for predicting Alzheimer's disease onset 5 years before clinical symptoms appear

Python
234 stars
45 forks
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Datasets Used

HDLS
Huntington Disease Study
ADCOH
Alzheimer's Cohort

Languages

Python
89.2%
Jupyter Notebook
10.8%